Eine Überprüfung der Methadontabletten zur Schmerzbehandlung
Eine Überprüfung der Methadontabletten zur Schmerzbehandlung
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The following information describes dosages that are commonly used or recommended. However, Beryllium sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to suit your needs.
The initial methadone dose should be carefully titrated to the individual. Too rapid titration for the patient's sensitivity is more likely to produce adverse effects.
Teratogenic Effects. Pregnancy Category Kohlenstoff – There are no controlled studies of methadone use in pregnant women that can Beryllium used to establish safety. However, an expert Nachprüfung of published data on experiences with methadone use during pregnancy by the Teratogen Information Organisation (TERIS) concluded that maternal use of methadone during pregnancy as parte of a supervised, therapeutic regimen is unlikely to Haltung a substantial teratogenic risk (quantity and quality of data assessed as “limited to fair”). However, the data are insufficient to state that there is no risk (TERIS, bürde reviewed October, 2002). Pregnant women involved hinein methadone maintenance programs have been reported to have significantly improved prenatal care leading to significantly reduced incidence of obstetric and fetal complications and neonatal morbidity and mortality when compared to women using illicit drugs.
Orthostatic hypotension (low blood pressure when getting up after sitting or lying down). Symptoms can include:
Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal (cause death).
Overdose in children warning: Children Weltgesundheitsorganisation accidentally take this drug have a high risk of death from overdosing. Children should not take this drug.
Abnormal fetal nonstress tests (NSTs) have been reported to occur more frequently when the test is performed 1 to 2 hours after a maintenance dose of methadone Methadontabletten online kaufen rein late pregnancy compared to controls.
Do not take a higher dose of methadone hydrochloride tablets or take it more often than prescribed. This can lead to an overdose and possible death.
Opioid antagonists should not Beryllium administered in the absence of clinically significant respiratory or cardiovascular depression. Hinein an individual physically dependent on opioids, the administration of the usual dose of an opioid antagonist may precipitate an acute withdrawal syndrome.
The safety and effectiveness of this drug hasn’t been established in children. It shouldn’t be used in children younger than 18 years.
The decrease in plasma half-life and increased clearance of methadone resulting in lower methadone trough levels during pregnancy can lead to withdrawal symptoms rein some pregnant patients. The dosage may need to be increased or the dosing interval decreased in pregnant patients receiving methadone (Teich PRECAUTIONS, Pregnancy, Labor and Delivery, and DOSAGE AND ADMINISTRATION).
Overdose rein children warning: Children who accidentally take this drug have a high risk of death from overdosing. Children should not take this drug.
Patients seeking to discontinue methadone maintenance treatment of opioid dependence should be apprised of the high risk of relapse to illicit drug use associated with discontinuation of methadone maintenance treatment.
Patients tolerant to other opioids may Beryllium incompletely tolerant to methadone. Incomplete cross-tolerance is of particular concern for patients tolerant to other mu-opioid agonists who are being converted to treatment with methadone, thus making determination of dosing during opioid treatment conversion complex. Deaths have been reported during conversion from chronic, high-dose treatment with other opioid agonists. Therefore, it is critical to understand the pharmacokinetics of methadone when converting patients from other opioids (Teich DOSAGE AND ADMINISTRATION, Table 1, for appropriate conversion schedules).